Monte Carlo Analysis on a Large Pedigree

Genet Epidemiol. 1993;10(6):677-82. doi: 10.1002/gepi.1370100658.

Abstract

Monte Carlo methods for linkage and segregation analysis are applied to the HGAR1 pedigree. To address these data, the methods are extended in several ways. The results are compared with those provided by PAP.

Publication types

  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Genetic Linkage*
  • Genetic Predisposition to Disease
  • Humans
  • Hypercholesterolemia / genetics
  • Infant
  • Infant, Newborn
  • Likelihood Functions
  • Lipids / genetics
  • Male
  • Middle Aged
  • Models, Genetic
  • Monte Carlo Method*
  • Pedigree*
  • Receptors, LDL / genetics

Substances

  • Lipids
  • Receptors, LDL