Primary low-grade B-cell lymphoma of the conjunctiva: a mucosa-associated lymphoid tissue type lymphoma

Histopathology. 1993 Nov;23(5):417-24. doi: 10.1111/j.1365-2559.1993.tb00489.x.


We describe the clinical presentation, morphology, immunophenotypic features and molecular biology of seven cases of conjunctival lymphoid infiltration. In five cases there was either immunophenotypic or molecular evidence of B-cell lymphoma. Each of these cases showed the morphological, immunophenotypic and molecular feature of low-grade B-cell lymphoma of mucosa-associated lymphoid tissue (MALT) type. The findings suggest that most conjunctival lymphomas are of this type and explains their uniformly favourable prognosis.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Conjunctival Neoplasms / genetics
  • Conjunctival Neoplasms / immunology
  • Conjunctival Neoplasms / pathology*
  • DNA, Neoplasm / genetics
  • Female
  • Gene Rearrangement, B-Lymphocyte, Heavy Chain
  • Humans
  • Lymphoid Tissue / pathology
  • Lymphoma, B-Cell / genetics
  • Lymphoma, B-Cell / immunology
  • Lymphoma, B-Cell / pathology*
  • Lymphoma, Non-Hodgkin / genetics
  • Lymphoma, Non-Hodgkin / immunology
  • Lymphoma, Non-Hodgkin / pathology*
  • Male
  • Middle Aged
  • Mucous Membrane / pathology
  • Prognosis


  • DNA, Neoplasm