Lead encephalopathy mimicking a cerebellar tumor

Acta Paediatr. 1993 Apr;82(4):423-5. doi: 10.1111/j.1651-2227.1993.tb12713.x.


Encephalopathy is a rare but severe complication of lead poisoning, mainly due to cerebral edema. Usually diffuse, symptoms and signs are sometimes focal, suggesting a false diagnosis of tumor, particularly cerebellar tumor. We report such a case diagnosed by MR imaging in which early treatment for edema avoided neurosurgical exploration. Only six cases have been published since Biemond and Van Creveld's first report in 1939. Several data--clinical and experimental--providing specific involvement of cerebellum in lead poisoning are emphasized.

Publication types

  • Case Reports

MeSH terms

  • Cerebellar Diseases / chemically induced
  • Cerebellar Diseases / diagnosis*
  • Cerebellar Neoplasms / diagnosis*
  • Child, Preschool
  • Diagnosis, Differential
  • Humans
  • Lead Poisoning / complications
  • Lead Poisoning / diagnosis*
  • Magnetic Resonance Imaging
  • Male