Long-term treatment of retinitis pigmentosa with acetazolamide. A pilot study

Graefes Arch Clin Exp Ophthalmol. 1993 May;231(5):254-6. doi: 10.1007/BF00919100.


The therapeutic effect of long-term treatment with acetazolamide (from 3 weeks to 16 months) of seven patients with retinitis pigmentosa was studied. Improvement in visual acuity was found in almost all the eyes, accompanied by an improvement in the macular threshold in two patients. The therapeutic effect was independent of reduction of macular edema, as judged by fluorescein angiography.

MeSH terms

  • Acetazolamide / therapeutic use*
  • Adult
  • Drug Administration Schedule
  • Edema / drug therapy
  • Female
  • Fluorescein Angiography
  • Fundus Oculi
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Pilot Projects
  • Retinal Diseases / drug therapy
  • Retinitis Pigmentosa / drug therapy*
  • Retinitis Pigmentosa / physiopathology
  • Visual Acuity
  • Visual Fields


  • Acetazolamide