Multiple areas of intestinal atresia associated with immunodeficiency and posttransfusion graft-versus-host disease

J Pediatr. 1993 Jul;123(1):93-5. doi: 10.1016/s0022-3476(05)81547-1.

Abstract

We describe an infant with multiple segmental areas of atresia of the small and large bowel, with histologic features characteristic of the hereditary form of the disease. Posttransfusion graft-versus-host disease developed first, and then immunodeficiency was found. This report confirms the association between hereditary multiple intestinal atresia and immunodeficiency. We recommend irradiation of blood products in patients with multiple intestinal atresia pending evaluation of immune system status.

Publication types

  • Case Reports

MeSH terms

  • Erythrocyte Transfusion*
  • Female
  • Graft vs Host Disease / etiology
  • Graft vs Host Disease / immunology
  • Graft vs Host Disease / pathology*
  • Humans
  • Immunologic Deficiency Syndromes / etiology
  • Immunologic Deficiency Syndromes / immunology
  • Immunologic Deficiency Syndromes / pathology*
  • Infant
  • Intestinal Atresia / complications
  • Intestinal Atresia / immunology
  • Intestinal Atresia / pathology*
  • Intestine, Large / abnormalities*
  • Intestine, Small / abnormalities*
  • Transfusion Reaction*