Abstract
Thirty-three clinical isolates of Bacteroides strains with a moderate-to-high level of resistance to 5-nitroimidazole were compared with three strains previously studied by Southern blotting of their DNA. Whether plasmid-borne or chromosomally determined, all genetic determinants that are resistant to 5-nitroimidazole belong to two hybridization groups.
MeSH terms
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Bacteroides / drug effects*
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Bacteroides / genetics
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Bacteroides / isolation & purification
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Bacteroides Infections / drug therapy
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Bacteroides Infections / microbiology
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Chromosomes, Bacterial
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Cloning, Molecular
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Conjugation, Genetic
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Drug Resistance, Microbial / genetics
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Genes, Bacterial
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Humans
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In Vitro Techniques
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Nitroimidazoles / pharmacology*
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R Factors
Substances
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Nitroimidazoles
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4-nitroimidazole