Asymptomatic cerebral involvement in Sjögren's syndrome: MRI findings of 15 cases

Neuroradiology. 1993;35(5):378-80. doi: 10.1007/BF00588375.


Fifteen patients with Sjögren's syndrome without clinical evidence of central nervous system disease were studied by MRI. Signal abnormalities were observed in 9 (60%). They were always visible on T2-weighted images as small punctate areas of high signal in the basal ganglia and the white matter of the cerebral hemispheres. Abnormalities were less frequently seen on T1-weighted images. Enlargement of cerebral sulci was observed in 6 cases. The specificity and significance of these abnormalities are discussed.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Atrophy
  • Brain / pathology
  • Brain Diseases / diagnosis*
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged
  • Prospective Studies
  • Sjogren's Syndrome / diagnosis*