Fertility and the cri du chat syndrome

Clin Genet. 1993 Apr;43(4):212-4. doi: 10.1111/j.1399-0004.1993.tb04467.x.


We describe a mother and daughter with typical cri du chat syndrome. Previous investigators have noted the lack of information about the reproductive fitness of patients with this disorder. This report demonstrates that females with cri du chat syndrome are fertile, can gestate and likewise deliver affected offspring, which has significant management and counseling implications.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Chromosome Banding
  • Chromosome Deletion
  • Chromosomes, Human, Pair 5*
  • Cri-du-Chat Syndrome / genetics*
  • Cri-du-Chat Syndrome / physiopathology
  • Female
  • Fertility*
  • Humans
  • Infant
  • Male
  • Pedigree