Abstract
The therapeutic effects of Salvia miltiorrhizae, Typha angustifolia, Rheum palmatum preparations on early renal damage of rats caused by fish bile were observed. These drugs were effective in reducing serum creatinine, urinary NAGase, count of necrosed epithelial cells of proximal tubule and that of glomerular filled with RBC in Bowman's space (P < 0.05), and also effective in increasing creatinine clearance (P < 0.05).
MeSH terms
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Acetylglucosaminidase / urine
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Acute Kidney Injury / etiology
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Acute Kidney Injury / prevention & control*
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Animals
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Bile
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Creatinine / blood
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Drugs, Chinese Herbal / therapeutic use*
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Fishes*
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Foodborne Diseases / drug therapy*
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Injections, Intraperitoneal
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Male
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Plant Extracts
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Plants, Medicinal
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Rats
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Rats, Sprague-Dawley
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Rheum
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Salvia miltiorrhiza
Substances
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Drugs, Chinese Herbal
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Plant Extracts
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Creatinine
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Acetylglucosaminidase