Inverting papilloma of the head and neck: the UCLA update

Otolaryngol Head Neck Surg. 1993 Jul;109(1):71-6. doi: 10.1177/019459989310900113.


Inverting papilloma of the nose and paranasal sinuses is a benign disease with malignant potential. This disease is characterized by multiple recurrences, especially after minimal operative therapy. Controversy exists over the most appropriate treatment for this rare tumor. This review presents an update of the UCLA experience with inverting papilloma over the past four decades along with a review of the literature. A retrospective study of 61 patients seen at the UCLA Medical Center was conducted. The mean age at presentation was 63 years, with a male-to-female ratio of 2:1. The most common symptom at presentation was nasal obstruction (71%), followed by epistaxis (27%). Seventeen percent of the patients in this series either had concurrent squamous cell carcinoma of the nose or paranasal sinuses, or it developed. Patients treated with a lateral rhinotomy and medial maxillectomy had a recurrence rate of 30 percent. Those treated with a less aggressive operation had a recurrence rate of 71 percent. Despite a trend for a more conservative sinus operation in recent literature, we continue to advocate a lateral rhinotomy and medial maxillectomy as the treatment of choice for inverting papilloma of the head and neck.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Carcinoma, Squamous Cell / complications
  • Carcinoma, Squamous Cell / epidemiology
  • Carcinoma, Squamous Cell / surgery*
  • Endoscopy
  • Epistaxis / epidemiology
  • Epistaxis / etiology
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Maxilla / surgery
  • Middle Aged
  • Nasal Obstruction / epidemiology
  • Nasal Obstruction / etiology
  • Neoplasm Recurrence, Local* / epidemiology
  • Nose Neoplasms / complications
  • Nose Neoplasms / epidemiology
  • Nose Neoplasms / surgery*
  • Papilloma / complications
  • Papilloma / epidemiology
  • Papilloma / surgery*
  • Paranasal Sinus Neoplasms / complications
  • Paranasal Sinus Neoplasms / epidemiology
  • Paranasal Sinus Neoplasms / surgery*
  • Retrospective Studies
  • Sex Factors
  • Treatment Outcome