Brucellosis: imported and laboratory-acquired cases, and an overview of treatment trials

Trans R Soc Trop Med Hyg. 1993 Mar-Apr;87(2):138-41. doi: 10.1016/0035-9203(93)90460-8.


Following the successful eradication of Brucella abortus infection in cattle, human brucellosis in England and Wales has become an uncommon imported disease. Culture of the organism presents a major laboratory hazard, and difficulties in identification may occur using a biochemical test-strip method. An overview of recent treatment trials of brucellosis indicates that regimens combining streptomycin and doxycycline are associated with a higher success rate (judged by the frequency of treatment failure and relapse following therapy) than combinations of rifampicin and doxycycline.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adolescent
  • Adult
  • Brucellosis / drug therapy
  • Brucellosis / epidemiology
  • Brucellosis / transmission*
  • England / epidemiology
  • Female
  • Humans
  • Incidence
  • Laboratory Infection / etiology*
  • Male
  • Travel
  • Wales / epidemiology