Configuration of tobacco mosaic virus, RNA during virus assembly

Nature. 1977 Jan 20;265(5591):217-9. doi: 10.1038/265217a0.

Abstract

When TMV reassembles, the uncoated RNA is folded back along the growing rod, probably down the central hole. This surprising configuration is essential for rapid elongation--presumably supplying RNA to its site of incorporation while keeping the bulk of the free RNA out of the way.

MeSH terms

  • Kinetics
  • Microscopy, Electron
  • Protein Binding
  • RNA, Viral* / metabolism
  • Tobacco Mosaic Virus / ultrastructure*
  • Viral Proteins / metabolism
  • Virus Replication*

Substances

  • RNA, Viral
  • Viral Proteins