Antigen-presenting cell types

Curr Opin Immunol. 1993 Jun;5(3):374-82. doi: 10.1016/0952-7915(93)90056-x.

Abstract

Different antigen-presenting cells elicit responses in different T-cell populations for primary activation, secondary stimulation and cytotoxic effector functions. Maturing bone marrow derived dendritic cells may acquire and process antigens, transport them to lymph nodes and activate naive T cells located there. By contrast, follicular dendritic cells, acquiring antigen-antibody complexes, maintain 'memory' via B-cell activation. Effector memory T cells recognize various tissue cells bearing antigen and we speculate that they may also target specialized antigen-presenting dendritic populations.

Publication types

  • Review

MeSH terms

  • Animals
  • Antigen-Presenting Cells* / immunology
  • Antigens / immunology
  • Antigens, CD / immunology
  • Bone Marrow Cells
  • Cell Movement
  • Cytotoxicity, Immunologic
  • Dendritic Cells / cytology
  • Dendritic Cells / immunology
  • HLA-D Antigens / immunology
  • Histocompatibility Antigens Class I / immunology
  • Humans
  • Immunologic Memory / physiology
  • Killer Cells, Natural / immunology
  • Lymph Nodes / cytology
  • Lymph Nodes / immunology
  • Lymphocyte Activation
  • Macrophages / immunology
  • Mice
  • Rats
  • T-Lymphocytes, Cytotoxic / immunology

Substances

  • Antigens
  • Antigens, CD
  • HLA-D Antigens
  • Histocompatibility Antigens Class I