Antiribosomal P protein antibodies in different populations of patients with systemic lupus erythematosus

Br J Rheumatol. 1993 Aug;32(8):663-5. doi: 10.1093/rheumatology/32.8.663.

Abstract

We report a significantly increased prevalence of antiribosomal P protein antibodies in Malaysian Chinese patients (38%) with SLE compared to white Caucasian (13%) and Afro-Caribbean (20%) patients. The increased prevalence was not due to a generalized increase in autoantibody production because anti-dsDNA and anti-SSA antibodies were present in comparable frequencies in the three ethnic groups while anti-Sm and anti-SSB antibodies were rarely found in the Malaysian Chinese patients.

Publication types

  • Comparative Study

MeSH terms

  • Antibodies, Anti-Idiotypic / analysis*
  • Antibodies, Antinuclear / analysis*
  • Asians*
  • Blacks*
  • Humans
  • Lupus Erythematosus, Systemic / blood
  • Lupus Erythematosus, Systemic / genetics
  • Lupus Erythematosus, Systemic / immunology*
  • Protozoan Proteins*
  • Ribosomal Proteins / immunology*
  • Whites*

Substances

  • Antibodies, Anti-Idiotypic
  • Antibodies, Antinuclear
  • L12E protein, Trypanosoma cruzi
  • Protozoan Proteins
  • Ribosomal Proteins