Vascular steal mimicking compression myelopathy in Paget's disease of bone: rapid reversal with calcitonin and systemic steroids

J Rheumatol. 1993 Jun;20(6):1064-5.

Abstract

Neurologic manifestations of Paget's disease of bone are primarily a result of mechanical compression on cranial nerves, spinal cord and roots. Less recognized is a myelopathy from "vascular steal" to highly vascularized and hypermetabolic pagetic bone. We describe a case of presumed ischemic myelitis in a patient with Paget's disease and aortic stenosis that was rapidly reversed with subcutaneous calcitonin and intravenous dexamethasone.

Publication types

  • Case Reports
  • Comparative Study

MeSH terms

  • Aged
  • Aortic Valve Stenosis / complications
  • Calcitonin / therapeutic use
  • Dexamethasone / therapeutic use
  • Diagnosis, Differential
  • Humans
  • Ischemia / complications
  • Ischemia / diagnosis*
  • Ischemia / drug therapy
  • Male
  • Myelitis / complications
  • Myelitis / diagnosis*
  • Myelitis / drug therapy
  • Osteitis Deformans / complications
  • Osteitis Deformans / diagnosis*
  • Osteitis Deformans / drug therapy
  • Spinal Cord / blood supply*

Substances

  • Dexamethasone
  • Calcitonin