Autism and hypomelanosis of Ito in twins

Dev Med Child Neurol. 1993 Sep;35(9):826-32. doi: 10.1111/j.1469-8749.1993.tb11734.x.

Abstract

A pair of monozygotic and a pair of dizygotic twins with autism and hypomelanosis of Ito skin-abnormalities are described. These observations are further evidence of the frequent association between these two conditions, already demonstrated in the literature, and suggest a possibly higher incidence of single gene associations among cases of autism with known genetic basis.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Autistic Disorder / complications
  • Autistic Disorder / diagnosis*
  • Autistic Disorder / physiopathology
  • Brain / diagnostic imaging
  • Brain / physiopathology
  • Corpus Callosum / diagnostic imaging
  • Corpus Callosum / physiopathology*
  • Humans
  • Karyotyping
  • Magnetic Resonance Imaging
  • Male
  • Melatonin / analysis*
  • Melatonin / metabolism
  • Metabolic Diseases / complications
  • Metabolic Diseases / physiopathology
  • Pigmentation Disorders / complications
  • Pigmentation Disorders / physiopathology*
  • Radiography
  • Twins, Monozygotic*

Substances

  • Melatonin