Recurrent apparent life-threatening events during infancy: a manifestation of inborn errors of metabolism

J Pediatr. 1993 Sep;123(3):415-8. doi: 10.1016/s0022-3476(05)81747-0.


To determine how often inborn errors of metabolism may cause unexplained apnea or recurrent apparent life-threatening events in infants, we retrospectively reviewed the records of 166 infants who were referred for apnea evaluation. A metabolic disorder was identified in 7 infants (4.2%), all of whom had recurrent apparent life-threatening events.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Apnea / etiology*
  • Apnea / mortality
  • Humans
  • Infant
  • Infant, Newborn
  • Metabolism, Inborn Errors / diagnosis
  • Metabolism, Inborn Errors / mortality
  • Metabolism, Inborn Errors / physiopathology*
  • Recurrence
  • Retrospective Studies