Effects of cardioplegic reperfusion on ATP recovery of rod-shaped myocytes isolated from rat ventricles

Jpn J Physiol. 1993;43(2):259-65. doi: 10.2170/jjphysiol.43.259.

Abstract

ATP content [ATP] and fraction of rod-shaped myocytes (Rrod) were measured in ventricular myocytes isolated from the rat heart. [ATP] (nmol (10(6) cells)-1) and Rrod (%) were 72.0 and 60.5, respectively, and significantly reduced to 18.8 and 41.8 by no-flow ischemia for 30 min. Reperfusion for 15 min with cardioplegic solutions restored [ATP] of rod-shaped myocytes to the control level.

MeSH terms

  • Adenosine Triphosphate / metabolism*
  • Animals
  • Cardioplegic Solutions
  • In Vitro Techniques
  • Kinetics
  • Myocardial Ischemia / metabolism
  • Myocardial Ischemia / pathology
  • Myocardial Reperfusion*
  • Myocardium / cytology
  • Myocardium / metabolism*
  • Rats
  • Rats, Sprague-Dawley

Substances

  • Cardioplegic Solutions
  • Adenosine Triphosphate