Immunosuppression in dogs naturally infected with Babesia gibsoni

J Vet Med Sci. 1993 Jun;55(3):503-5. doi: 10.1292/jvms.55.503.


We examined lymphoproliferative response to phytohemagglutinin and anti-parasite antibody level in dogs naturally infected with Babesia gibsoni. The dogs with subclinical B. gibsoni infection exhibited suppressed lymphocyte blastogenesis. Prominent depression of lymphocyte blastogenesis and anti-parasite antibody production was observed in dogs suffering from relapses of clinical B. gibsoni infection.

Publication types

  • Case Reports

MeSH terms

  • Animals
  • Antibodies, Protozoan / blood
  • Antibody Formation
  • Babesiosis / immunology*
  • Dog Diseases*
  • Dogs / immunology*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Immune Tolerance*
  • Lymphocyte Activation
  • Male
  • Reference Values


  • Antibodies, Protozoan