Liver involvement in giant cell arteritis

Clin Rheumatol. 1993 Jun;12(2):219-22. doi: 10.1007/BF02231530.

Abstract

Giant cell arteritis is a vasculitis which usually affects large and medium-sized vessels in patients over 50 years old. The liver is one of the internal organs which can be involved in this systemic disease. During the last 15 years, 56 patients with giant cell arteritis were seen in our hospital. In 12 patients disturbed liver function test were found. In the majority of cases the disturbance was of cholestatic type and resolved completely with steroid treatment. The association of temporal arteritis with disturbed liver function tests is discussed, with a review of the recent literature.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Aged
  • Aged, 80 and over
  • Female
  • Giant Cell Arteritis / drug therapy
  • Giant Cell Arteritis / enzymology
  • Giant Cell Arteritis / physiopathology*
  • Humans
  • Liver / drug effects
  • Liver / enzymology
  • Liver / physiopathology*
  • Liver Function Tests
  • Male
  • Middle Aged
  • Retrospective Studies
  • Steroids / therapeutic use

Substances

  • Steroids