Long-term outcome of acute pancreatitis: a prospective study with 118 patients

Digestion. 1993;54(3):143-7. doi: 10.1159/000201028.


118 patients who had recovered from acute pancreatitis underwent endoscopic retrograde pancreatography (ERCP) during a long-term follow-up (mean 4.4 years, range 1-17) to investigate the frequency and features of residual ductal lesions. Oedematous and necrohaemorrhagic pancreatitis occurred in 35 and in 83 patients, respectively. The aetiology was biliary (39 patients), alcoholic (32), biliary-alcoholic (18) and miscellaneous (29). After oedematous pancreatitis, ERCP was normal in 31, showed obstructive pancreatitis in 2 and a slight localized and smooth stricture of the main duct in 2 patients. After necrotizing pancreatitis, 29 patients showed ductal changes without features of chronic pancreatitis, 7 obstructive, 3 chronic calcifying pancreatitis and 44 normal pictures. In 17 patients submitted to two or three ERCPs during a mean 10-year follow-up, the ductal appearance was unchanged in 12, worsened in 3, and improved in 2 patients. The aetiology of pancreatitis and frequency of recurrences was similar in patients with or without scarring lesions. We conclude that residual ductal lesions are common after acute necrotizing pancreatitis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Alcoholism / complications
  • Biliary Tract Diseases / complications
  • Cholangiopancreatography, Endoscopic Retrograde
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Pancreatic Ducts / diagnostic imaging
  • Pancreatitis / diagnostic imaging
  • Pancreatitis / epidemiology*
  • Pancreatitis / etiology
  • Prospective Studies
  • Time Factors