Antifungal macrocyclic polylactones from Penicillium verruculosum
- PMID: 8360106
- DOI: 10.7164/antibiotics.46.1101
Antifungal macrocyclic polylactones from Penicillium verruculosum
Abstract
Three macrocyclic polylactones have been isolated from Penicillium verruculosum. Two were found to be novel and the third to be identical with NG-012(1). Their structures were elucidated by spectroscopic and chemical methods. A full assignment of 1H- and 13C-resonances in acetone-d6 are given for all three compounds. The compounds show antifungal activity.
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