Optic nerve hypoplasia with good visual acuity and visual field defects: a study of children of diabetic mothers

Arch Ophthalmol. 1977 Feb;95(2):254-8. doi: 10.1001/archopht.1977.04450020055011.


Seventeen children, born of severely diabetic mothers, exhibited segmental optic nerve hypoplasia with normal visual acuity and altitudinal or sector field defects corresponding to the hypoplastic areas of the disc. This is the first group of patients with optic nerve hypoplasia in which a possible cause has been identified. Optic nerve hypoplasia is neither a rare abnormality usually associated with serious central nervous system defects, nor is it always accompanied by decreased visual acuity.

MeSH terms

  • Abducens Nerve
  • Adolescent
  • Child
  • Child, Preschool
  • Diabetes Complications*
  • Female
  • Humans
  • Lacrimal Duct Obstruction
  • Male
  • Nystagmus, Pathologic / etiology
  • Optic Nerve / abnormalities*
  • Optic Nerve Diseases / etiology
  • Paralysis / etiology
  • Strabismus / etiology
  • Trochlear Nerve
  • Visual Acuity*
  • Visual Fields*