Long-term results of treatment for axillary subclavian vein thrombosis

Can J Surg. 1993 Aug;36(4):365-71.

Abstract

Thrombolytic therapy is an effective method for reopening an occluded venous segment, but little is known about the long-term results of thrombolysis via direct intravenous route for axillary subclavian vein thrombosis (ASVT). Our experience with 13 cases of primary ASVT illustrates the possible advantages of a protocol consisting of lytic therapy, surgical decompression and percutaneous balloon angioplasty if a high-grade stenosis persists. If accompanied by adjunctive therapy to correct the underlying cause, thrombolytic therapy for ASVT results in acceptable long-term symptom relief and vein patency.

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon / methods*
  • Anticoagulants / therapeutic use
  • Axilla / blood supply*
  • Causality
  • Clinical Protocols
  • Combined Modality Therapy
  • Female
  • Follow-Up Studies
  • Hot Temperature / therapeutic use
  • Humans
  • Infusions, Intravenous
  • Male
  • Middle Aged
  • Phlebography
  • Streptokinase / therapeutic use*
  • Subclavian Vein*
  • Thrombectomy / methods*
  • Thrombolytic Therapy / methods*
  • Thrombosis / classification
  • Thrombosis / diagnostic imaging
  • Thrombosis / epidemiology
  • Thrombosis / therapy*
  • Treatment Outcome
  • Urokinase-Type Plasminogen Activator / therapeutic use*
  • Vascular Patency
  • Veins / transplantation

Substances

  • Anticoagulants
  • Streptokinase
  • Urokinase-Type Plasminogen Activator