Congenital aortic stenosis and pregnancy--a reappraisal

Am J Obstet Gynecol. 1993 Sep;169(3):540-5. doi: 10.1016/0002-9378(93)90616-q.


Objective: This study was performed to determine the maternal and fetal outcome in pregnant patients with congenital aortic stenosis without previous valvular replacement.

Study design: A retrospective review of 25 pregnancies in 13 patients delivered at our centers from September 1976 to September 1992 was undertaken.

Results: Five (38%) patients had associated congenital heart lesions, three (23%) had severe stenosis (echocardiographically estimated valve area < or = 0.7 cm2), two had prior open aortic valve commissurotomy, and one had balloon valvuloplasty during pregnancy. There were no maternal deaths. Of the 25 pregnancies, five (20%) resulted in therapeutic abortions. There was no perinatal mortality, preterm labor, or increased incidence of pregnancy complications or fetal growth retardation in the remaining 20 pregnancies. One infant (5%) had congenital heart disease.

Conclusion: Pregnancy outcome is generally satisfactory in patients with congenital aortic stenosis.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Adult
  • Aortic Valve Stenosis / complications*
  • Aortic Valve Stenosis / congenital
  • Aortic Valve Stenosis / surgery
  • Echocardiography
  • Female
  • Fetal Death
  • Humans
  • Maternal Mortality
  • Pregnancy
  • Pregnancy Complications, Cardiovascular* / surgery
  • Pregnancy Outcome*
  • Retrospective Studies
  • Ventricular Function