A recurring translocation, t(11;22)(p13;q11.2), characterizes intra-abdominal desmoplastic small round-cell tumors

Cancer Genet Cytogenet. 1993 Aug;69(1):17-21. doi: 10.1016/0165-4608(93)90105-u.


We report the cytogenetic analysis of two cases of intra-abdominal desmoplastic small round-cell tumor, one of which had a t(11;22)(p13;q11.2) translocation. The same translocation has previously been reported in two other cases analyzed cytogenetically, indicating that it could be a consistent abnormality characteristic of this rare tumor entity.

Publication types

  • Case Reports

MeSH terms

  • Abdominal Neoplasms / drug therapy
  • Abdominal Neoplasms / genetics*
  • Abdominal Neoplasms / surgery
  • Adult
  • Chromosomes, Human, Pair 11*
  • Chromosomes, Human, Pair 22*
  • Combined Modality Therapy
  • Humans
  • Karyotyping
  • Male
  • Translocation, Genetic*