Two human breast tumors with translocations involving 12q13-15 as the sole cytogenetic abnormality

Cancer Genet Cytogenet. 1993 Aug;69(1):68-71. doi: 10.1016/0165-4608(93)90117-5.


Two benign epithelial breast lesions showing clonal chromosomal alterations involving 12q13-15 are reported. As the only clonal aberration a t(12;14)(q13-14;q24) was noted in a florid epithelial hyperplasia with extended adenosis. A t(10;12)(p14-15;q13) was found in a papilloma also with areas of florid epithelial hyperplasia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / pathology
  • Cells, Cultured
  • Chromosome Banding
  • Chromosomes, Human, Pair 10
  • Chromosomes, Human, Pair 12*
  • Chromosomes, Human, Pair 14
  • Female
  • Humans
  • Karyotyping
  • Translocation, Genetic*