Gamete intrafallopian transfer: ethical considerations, historical development of the procedure, and comparison with other advanced reproductive technologies

Fertil Steril. 1993 Sep;60(3):389-402. doi: 10.1016/s0015-0282(16)56148-2.


Objective: To report on ethical considerations regarding GIFT as well as the developmental history of the procedure and to review the literature and compare it with other advanced reproductive technologies (ARTs).

Design: Indications, patient screening, recent evaluations, methods of ovarian hyperstimulation and oocyte retrieval-assessment, gamete transfer and pregnancy outcome are discussed in this review. A comparison of GIFT with other ARTs is also attempted.

Main outcome measures: Gamete intrafallopian transfer pregnancy determination and outcome.

Conclusions: Gamete intrafallopian transfer is an ethically acceptable procedure by different religious groups. In a selected group of patients, GIFT is an acceptable and, in some occasions, a preferable procedure to other ARTs.

Publication types

  • Comparative Study
  • Review

MeSH terms

  • Biomarkers
  • Embryo Transfer
  • Ethics, Medical*
  • Female
  • Fertilization in Vitro / methods
  • Gamete Intrafallopian Transfer / trends*
  • Humans
  • Male
  • Personnel Selection
  • Pregnancy
  • Pregnancy Outcome
  • Pregnancy Tests
  • Reproductive Techniques*
  • Specimen Handling


  • Biomarkers