Cytomegalovirus infections of the oral cavity. A report of six cases and review of the literature

Oral Surg Oral Med Oral Pathol. 1993 Jan;75(1):76-85. doi: 10.1016/0030-4220(93)90410-6.


Cytomegalovirus is responsible for a significant percentage of asymptomatic viral infections worldwide. Although virtually any cell or organ may be infected, involvement of the oral cavity is uncommon. Only nine well-documented examples of intraoral cytomegalovirus infections were found in a review of the English-language literature. We report six additional examples, five of which possessed unique clinical and histopathologic characteristics. The light and electron-microscopic features of cytomegalovirus are discussed, as well as diagnostic adjuncts such as immunohistochemistry and deoxyribonucleic acid in situ hybridization.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Acquired Immunodeficiency Syndrome / complications
  • Adult
  • Aged
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Infections* / etiology
  • Cytomegalovirus Infections* / microbiology
  • Cytomegalovirus Infections* / pathology
  • DNA, Viral / analysis
  • HIV Seropositivity / complications
  • Histoplasmosis / complications
  • Humans
  • In Situ Hybridization
  • Inclusion Bodies, Viral
  • Male
  • Middle Aged
  • Mouth Diseases / etiology
  • Mouth Diseases / microbiology*
  • Mouth Diseases / pathology
  • Sarcoma, Kaposi / complications
  • Stomatitis, Herpetic / complications


  • DNA, Viral