Abstract
Partially introduction of the biguanide structure into heterocyclic systems leads to various substituted 2-guanidino-4(3H)-chinazolinones. The compounds exhibit significant antimycotic and gyrase-inhibiting activities.
MeSH terms
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / pharmacology
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Candida albicans / drug effects
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Microbial Sensitivity Tests
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Quinazolines / chemical synthesis*
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Topoisomerase II Inhibitors*
Substances
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Antifungal Agents
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Quinazolines
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Topoisomerase II Inhibitors