Pathogenesis and pathology

Clin Chest Med. 1993 Mar;14(1):17-30.

Abstract

Pathogenesis consists of a discussion of the role of oncogenes and suppressor genes on small-cell lung cancer and non-small-cell lung cancer as well as the external factors of smoking (active and passive), asbestos, and radon. Pathology consists of discussion of squamous cell lung cancer, adenocarcinoma and bronchoalveolar carcinoma, large cell carcinoma (including giant cell and clear cell variants), and neuroendocrine tumors. Mesotheliomas are discussed as is the role of monoclonal antibodies in diagnosis.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / etiology
  • Adenocarcinoma / pathology
  • Asbestos / adverse effects*
  • Carcinoma, Non-Small-Cell Lung / pathology
  • Carcinoma, Small Cell / pathology
  • Carcinoma, Squamous Cell / etiology
  • Carcinoma, Squamous Cell / pathology
  • Female
  • Humans
  • Lung Neoplasms / etiology*
  • Lung Neoplasms / genetics
  • Lung Neoplasms / pathology
  • Male
  • Mesothelioma / pathology
  • Oncogenes / genetics*
  • Radon / adverse effects*
  • Smoking / adverse effects*

Substances

  • Asbestos
  • Radon