Abstract
A total of 3,250 serum specimens collected in England in 1991 and 1992 were tested by an indirect enzyme-linked immunosorbent assay for antibody to Norwalk virus using baculovirus-expressed capsid antigen, and 2,382 (73.3%) were positive. The prevalence of Norwalk virus antibody differed regionally. It was lowest (24.6%) in 6- to 11-month-old infants and increased to 89.7% in persons over 60 years old.
Publication types
-
Research Support, U.S. Gov't, P.H.S.
MeSH terms
-
Adolescent
-
Adult
-
Age Factors
-
Aged
-
Aged, 80 and over
-
Antibodies, Viral / blood*
-
Antigens, Viral / immunology*
-
Baculoviridae / genetics
-
Capsid / immunology*
-
Child
-
Child, Preschool
-
England / epidemiology
-
Enzyme-Linked Immunosorbent Assay
-
Female
-
Humans
-
Infant
-
Infant, Newborn
-
Male
-
Middle Aged
-
Norwalk virus / immunology*
-
Prevalence
-
Recombinant Proteins / immunology
-
Virus Diseases / epidemiology*
Substances
-
Antibodies, Viral
-
Antigens, Viral
-
Recombinant Proteins