Combined central and peripheral acute demyelination

Ital J Neurol Sci. 1993 Jan;14(1):83-6. doi: 10.1007/BF02339047.

Abstract

We describe a patient with multiple sclerosis who had a bout of central demyelination associated with an acute inflammatory demyelinating polyneuropathy. The contemporary involvement of central and peripheral nervous system due to a demyelinating disease has been reported anecdotically in humans, and can be induced experimentally in animals. It may be sustained by a common pathogenetic factor.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain / pathology
  • Central Nervous System Diseases / complications
  • Central Nervous System Diseases / drug therapy
  • Central Nervous System Diseases / pathology*
  • Demyelinating Diseases / complications
  • Demyelinating Diseases / drug therapy
  • Demyelinating Diseases / pathology*
  • Electroencephalography
  • Electromyography
  • Female
  • Humans
  • Magnetic Resonance Imaging
  • Motor Neurons / physiology
  • Movement Disorders / etiology
  • Neural Conduction
  • Neurons, Afferent / physiology
  • Peripheral Nervous System Diseases / complications
  • Peripheral Nervous System Diseases / drug therapy
  • Peripheral Nervous System Diseases / pathology*
  • Prednisone / therapeutic use

Substances

  • Prednisone