Gender, age, usual weight, and tobacco use as predictors of weight loss in patients with lung cancer

Oncol Nurs Forum. 1993 Apr;20(3):466-72.


The purpose of this study was to examine the relationships of gender, age, usual weight, and tobacco use with cancer-related weight loss, food intake, and resting energy expenditure. Data were collected from medical records, interviews, self-report diet records, indirect calorimetry, and 40K counting. A convenience sample consisted of 60 subjects with non-small cell lung cancer who were at least one month postradiotherapy. Mean weight loss was 2 kg at diagnosis and 6 kg at six weeks postradiotherapy. Partial correlations, controlling for stage of disease, indicated that gender, age, and current smoking correlate significantly with cancer-related weight loss and decreased food intake. Gender, age, and current smoking accounted for 21% of the variance of weight loss postradiotherapy over and above stage of disease. Potential practice implications focus on enhanced nutritional assessment and early intervention for men, the elderly, and current smokers, who are at higher risk for weight loss.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Activities of Daily Living
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Body Mass Index
  • Calorimetry, Indirect
  • Carcinoma, Non-Small-Cell Lung / epidemiology
  • Carcinoma, Non-Small-Cell Lung / physiopathology*
  • Carcinoma, Non-Small-Cell Lung / radiotherapy
  • Cell Differentiation
  • Combined Modality Therapy
  • Diet Surveys
  • Energy Intake
  • Energy Metabolism
  • Female
  • Humans
  • Lung Neoplasms / epidemiology
  • Lung Neoplasms / physiopathology*
  • Lung Neoplasms / radiotherapy
  • Male
  • Middle Aged
  • Neoplasm Staging
  • Outcome Assessment, Health Care
  • Predictive Value of Tests
  • Quality of Life
  • Sex Factors
  • Smoking / adverse effects*
  • Weight Loss*