Ras-related proteins

Curr Opin Cell Biol. 1993 Apr;5(2):265-8. doi: 10.1016/0955-0674(93)90114-6.

Abstract

A combination of genetic and biochemical techniques has revealed key players in the Ras signal transduction pathway that link receptors to growth and differentiation. Rho and Rac have been shown to couple extracellular signals to the organization of the actin cytoskeleton, while ADP ribosylation factor is required for the formation of non-clathrin coated vesicles.

Publication types

  • Review

MeSH terms

  • ADP-Ribosylation Factors
  • Animals
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Cytoskeleton / metabolism
  • GTP-Binding Proteins
  • Humans
  • Mitogen-Activated Protein Kinase 1
  • Models, Biological
  • Protein Kinases
  • Protein Serine-Threonine Kinases
  • Protein-Tyrosine Kinases
  • Proto-Oncogene Proteins p21(ras)*
  • Rho Factor
  • Signal Transduction*

Substances

  • Rho Factor
  • Protein Kinases
  • Protein-Tyrosine Kinases
  • Protein Serine-Threonine Kinases
  • Calcium-Calmodulin-Dependent Protein Kinases
  • Mitogen-Activated Protein Kinase 1
  • GTP-Binding Proteins
  • ADP-Ribosylation Factors
  • HRAS protein, human
  • Proto-Oncogene Proteins p21(ras)