Successful treatment of simultaneous pulmonary Pseudallescheria boydii and Aspergillus terreus infection with oral itraconazole

Clin Infect Dis. 1993 Jun;16(6):803-5. doi: 10.1093/clind/16.6.803.

Abstract

Pseudallescheria boydii and Aspergillus terreus are unusual opportunistic fungal pathogens that are often resistant to chemotherapy with amphotericin B. We report a case of simultaneous invasive pulmonary infection with these organisms occurring in a bone marrow transplant recipient who was successfully treated with the oral azole itraconazole.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adult
  • Antifungal Agents / administration & dosage
  • Antifungal Agents / therapeutic use*
  • Aspergillosis / drug therapy*
  • Aspergillosis / etiology
  • Aspergillosis / surgery
  • Aspergillus / drug effects
  • Bone Marrow Transplantation / adverse effects
  • Bone Marrow Transplantation / immunology
  • Debridement
  • Graft vs Host Disease / complications
  • Graft vs Host Disease / etiology
  • Humans
  • Immunocompromised Host
  • Itraconazole
  • Ketoconazole / administration & dosage
  • Ketoconazole / analogs & derivatives*
  • Ketoconazole / pharmacology
  • Ketoconazole / therapeutic use
  • Lung / diagnostic imaging
  • Lung / microbiology
  • Lung Diseases, Fungal / drug therapy*
  • Lung Diseases, Fungal / etiology
  • Lung Diseases, Fungal / surgery
  • Male
  • Microbial Sensitivity Tests
  • Mycetoma / drug therapy*
  • Mycetoma / etiology
  • Mycetoma / surgery
  • Opportunistic Infections / drug therapy
  • Opportunistic Infections / etiology
  • Opportunistic Infections / surgery
  • Pseudallescheria* / drug effects
  • Tomography, X-Ray Computed
  • Transplantation, Autologous

Substances

  • Antifungal Agents
  • Itraconazole
  • Ketoconazole