Wilms' tumor in the Li-Fraumeni cancer family syndrome

Cancer Genet Cytogenet. 1993 Jun;67(2):133-5. doi: 10.1016/0165-4608(93)90166-j.


Scrutiny of the family pedigrees of a population-based series of 176 children diagnosed with Wilms' tumor between 1954 and 1990, along with a review of the literature on the Li-Fraumeni cancer family syndrome, indicate that Wilms' tumor may be an uncommon component of the syndrome and that a small proportion of children with Wilms' tumor may be members of Li-Fraumeni syndrome (LFS) families.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Child
  • Child, Preschool
  • Humans
  • Infant
  • Pedigree
  • Syndrome
  • Wilms Tumor / genetics*