The prevalence of type 1 diabetes mellitus at follow-up of Swedish infants congenitally infected with cytomegalovirus

Diabet Med. 1993 Jul;10(6):521-3. doi: 10.1111/j.1464-5491.1993.tb00113.x.

Abstract

In a Swedish prospective study of congenital cytomegalovirus (CMV) infection, 76 infants were shown to be infected among 16,474 newborns screened by virus isolation in urine. Seventy-three of the excreters were followed up and one developed Type 1 diabetes, as compared to 38 of the 19,483 children born during the same period (p = 0.14, Fisher's one-tailed test). Thus we found no evidence that the combined finding of congenital CMV infection and Type 1 diabetes mellitus was related.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Autoantibodies / blood
  • C-Peptide / blood
  • Cytomegalovirus / isolation & purification
  • Cytomegalovirus Infections / congenital
  • Cytomegalovirus Infections / epidemiology*
  • Cytomegalovirus Infections / urine
  • Diabetes Mellitus, Type 1 / blood
  • Diabetes Mellitus, Type 1 / diagnosis
  • Diabetes Mellitus, Type 1 / epidemiology*
  • Follow-Up Studies
  • Glucagon
  • Glucose Tolerance Test
  • Humans
  • Infant, Newborn
  • Islets of Langerhans / immunology
  • Male
  • Prevalence
  • Sweden / epidemiology

Substances

  • Autoantibodies
  • C-Peptide
  • islet cell antibody
  • Glucagon