[DNA as a prognostic factor in colorectal cancer. A retrospective analysis of 34 patients]

Rev Esp Enferm Dig. 1993 Aug;84(2):100-4.
[Article in Spanish]


Objective: We study the tumoral DNA as a prognostic factor in patients operated for colo-rectal cancer.

Design: Retrospective. We analyze by flow cytometry the DNA content of tumoral tissue: Ploidy, DNA Index, Proliferative Index, S Phase.

Patients: 34 operated patients, for colo-rectal cancer, with a minimum 3 years of follow-up.

Results: Ploidy doesn't show any relation with other prognostic factors. Only Dukes C aneuploid patients had more positive nodes than diploid. Ploidy was not related to better evolution or survival. Neither DNA Index, Proliferative Index and S Phase were related to the evolution of the disease.

Conclusions: The DNA study by flow cytometry has no better prognostic value then other classical factors.

Publication types

  • English Abstract

MeSH terms

  • Aged
  • Aged, 80 and over
  • Colorectal Neoplasms / chemistry
  • Colorectal Neoplasms / genetics*
  • DNA, Neoplasm / analysis*
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Middle Aged
  • Ploidies
  • Prognosis
  • Retrospective Studies


  • DNA, Neoplasm