Low-carbohydrate diet optic neuropathy

Med J Aust. 1977 Jan 15;1(3):65-6.


Visual loss occurring in two patients taking prolonged carbohydrate-restrictive diets is reported. The clinical data in these patients point to a specific diet deficiency of thiamine, causing a bilateral optic neuropathy. A discussion of current concepts of thiamine deficiency in neuroophthalmic disorders is presented. It is recommended that patients on low-carbohydrate diets for prolonged periods of time should receive thiamine supplements.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Diet, Reducing / adverse effects*
  • Dietary Carbohydrates*
  • Humans
  • Male
  • Optic Nerve Diseases / etiology*
  • Thiamine Deficiency / complications*


  • Dietary Carbohydrates