Telomeric fusions in a Wilms' tumor

Cancer Genet Cytogenet. 1993 Sep;69(2):141-5. doi: 10.1016/0165-4608(93)90092-z.

Abstract

The present report describes the karyotypic findings in cells from a Wilms' tumor. The most consistent cytogenetic abnormalities detected consisted of translocations involving break and fusion of chromosomal telomeres and telomeric associations frequently affecting the terminus of the short arms of chromosomes 14 and 17.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Child, Preschool
  • Chromosome Aberrations*
  • Chromosome Banding
  • Chromosomes, Human, Pair 14
  • Chromosomes, Human, Pair 17
  • Humans
  • Karyotyping
  • Kidney Neoplasms / genetics*
  • Kidney Neoplasms / pathology
  • Male
  • Telomere / ultrastructure*
  • Translocation, Genetic*
  • Wilms Tumor / genetics*
  • Wilms Tumor / pathology