Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization

V Najfeld; J Menninger; D Muhleman; D E Comings; S L Gupta

doi:10.1159/000133584

Localization of indoleamine 2,3-dioxygenase gene (INDO) to chromosome 8p12-->p11 by fluorescent in situ hybridization

Cytogenet Cell Genet. 1993;64(3-4):231-2. doi: 10.1159/000133584.

Authors

V Najfeld¹, J Menninger, D Muhleman, D E Comings, S L Gupta

Affiliation

¹ Tumor Cytogenetics Laboratory, Mount Sinai Medical Center, New York, NY 10029.

PMID: 8404046
DOI: 10.1159/000133584

Abstract

Indolamine 2,3-dioxygenase and tryptophan 2,3-dioxygenase are two enzymes that degrade tryptophan to N-formylkynurenine. The gene (TDO2) for tryptophane 2,3-dioxygenase has been localized to 4q31-->32. We now report localization of INDO (the gene encoding indolamine 2,3-dioxygenase) by fluorescent in situ hybridization to 8p12-->p11.

Publication types

Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, P.H.S.

MeSH terms

Chromosomes, Human, Pair 8*
Humans
In Situ Hybridization, Fluorescence
Tryptophan Oxygenase / genetics*

Substances

Tryptophan Oxygenase

Grants and funding

CA 29991/CA/NCI NIH HHS/United States