Repeated inhalation of nebulized albuterol did not induce arrhythmias in a patient with Wolff-Parkinson-White syndrome and asthma

Chest. 1993 Jun;103(6):1892-4. doi: 10.1378/chest.103.6.1892.


It has been assumed that in asthmatic patients with Wolff-Parkinson-White (WPW) syndrome, ablative therapy for the condition is necessary for the safe treatment of the asthma with beta 2-adrenergic drugs. The following case report illustrates that inhaled albuterol was safely administered to an asthmatic patient with electrocardiographic evidence of preexcitation, without the need of an ablative procedure. This case report is, to our knowledge, the first in the literature in which the cardiac rhythm of a patient with WPW syndrome was monitored during repeated inhalations of a beta 2-agonist.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adult
  • Albuterol / administration & dosage*
  • Arrhythmias, Cardiac / chemically induced*
  • Asthma / complications
  • Asthma / drug therapy*
  • Contraindications
  • Electrocardiography
  • Female
  • Humans
  • Wolff-Parkinson-White Syndrome / complications*
  • Wolff-Parkinson-White Syndrome / physiopathology


  • Albuterol