The human pancreatic lipase-encoding gene: structure and conservation of an Alu sequence in the lipase gene family

Gene. 1993 Sep 15;131(2):281-5. doi: 10.1016/0378-1119(93)90307-o.

Abstract

The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Base Sequence
  • Conserved Sequence*
  • Exons
  • Humans
  • Introns
  • Lipase / chemistry
  • Lipase / genetics*
  • Molecular Sequence Data
  • Multigene Family*
  • Pancreas / enzymology*
  • Protein Conformation
  • Pseudogenes
  • Repetitive Sequences, Nucleic Acid*
  • Sequence Homology, Nucleic Acid

Substances

  • Lipase

Associated data

  • GENBANK/L11242
  • GENBANK/L24502
  • GENBANK/L24522
  • GENBANK/L24523
  • GENBANK/L24524
  • GENBANK/L24525
  • GENBANK/L24526
  • GENBANK/L24527
  • GENBANK/L24528
  • GENBANK/L24529