Abstract
The isolation and characterization of the human gene (hPL) encoding pancreatic lipase is reported. The gene has 13 exons dispersed in about 20 kb of genomic DNA. A pseudogene of hPL was also partially characterized. An Alu sequence is conserved in the homologous introns of hPL and the lipoprotein lipase-encoding gene.
Publication types
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Base Sequence
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Conserved Sequence*
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Exons
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Humans
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Introns
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Lipase / chemistry
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Lipase / genetics*
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Molecular Sequence Data
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Multigene Family*
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Pancreas / enzymology*
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Protein Conformation
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Pseudogenes
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Repetitive Sequences, Nucleic Acid*
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Sequence Homology, Nucleic Acid
Associated data
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GENBANK/L11242
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GENBANK/L24502
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GENBANK/L24522
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GENBANK/L24523
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GENBANK/L24524
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GENBANK/L24525
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GENBANK/L24526
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GENBANK/L24527
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GENBANK/L24528
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GENBANK/L24529