Gamma globulin re-treatment in Kawasaki disease

J Pediatr. 1993 Oct;123(4):657-9. doi: 10.1016/s0022-3476(05)80972-2.


We retrospectively reviewed the effects of intravenous gamma-globulin (IVGG) re-treatment of 13 children with Kawasaki disease and persistent or recrudescent fever. Fever and mucocutaneous inflammation resolved within 48 hours in nine patients; fever abated in two other children after a third course of IVGG. We conclude that IVGG re-treatment of Kawasaki disease appears to be safe and may improve the clinical course.

MeSH terms

  • Child, Preschool
  • Female
  • Humans
  • Immunoglobulins, Intravenous / therapeutic use*
  • Male
  • Mucocutaneous Lymph Node Syndrome / epidemiology
  • Mucocutaneous Lymph Node Syndrome / therapy*
  • Retrospective Studies
  • Treatment Failure


  • Immunoglobulins, Intravenous