Cross-modal associations and the human amygdala

Neuropsychologia. 1993 Aug;31(8):727-44. doi: 10.1016/0028-3932(93)90125-j.

Abstract

The role of the human amygdala in cross-modal associations was investigated in two subjects: SM-046, who had bilateral damage circumscribed to the amygdala; and the patient known as Boswell, whose damage in both temporal lobes includes the amygdala and surrounding cortices. Neither subject was impaired on Tactile-Visual or Visual-Tactile cross-modal tasks using the Arc-Circle test, suggesting that the amygdala is not involved in cross-modal associations involving perceptually "equivalent" basic stimulus properties. On the other hand, the results are compatible with the amygdala's involvement in higher-order associations between exteroceptive sensory data and interoceptive data concerned with correlated somatic states.

Publication types

  • Case Reports
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Amnesia / physiopathology
  • Amygdala / physiopathology*
  • Association Learning / physiology*
  • Brain Damage, Chronic / genetics
  • Brain Damage, Chronic / physiopathology*
  • Brain Mapping
  • Chromosome Aberrations / genetics
  • Chromosome Disorders
  • Dominance, Cerebral / physiology
  • Encephalitis / physiopathology
  • Female
  • Genes, Recessive
  • Herpes Simplex / physiopathology
  • Hippocampus / physiopathology
  • Humans
  • Male
  • Mental Recall / physiology*
  • Middle Aged
  • Neuropsychological Tests
  • Pattern Recognition, Visual / physiology*
  • Pregnancy
  • Size Perception / physiology
  • Stereognosis / physiology*
  • Syndrome
  • Temporal Lobe / physiopathology