Meconium staining and the meconium aspiration syndrome. Unresolved issues

Pediatr Clin North Am. 1993 Oct;40(5):955-81. doi: 10.1016/s0031-3955(16)38618-7.


Meconium staining of the amniotic fluid and the meconium aspiration syndrome will likely remain common occurrences faced by health care providers. Unfortunately, our understanding of these entities is incomplete. There are a number of issues which need to be adequately evaluated regarding the pathophysiology of MAS, the delivery room management of the meconium-stained infant, and the neonatal intensive care unit management of MAS. Currently, there is much dogma in various hospitals throughout this country regarding these issues, dogma which has yet to be substantiated by quality scientific investigations.

Publication types

  • Review

MeSH terms

  • Humans
  • Infant, Newborn
  • Intubation, Intratracheal
  • Meconium Aspiration Syndrome / physiopathology
  • Meconium Aspiration Syndrome / therapy*
  • Meconium*
  • Pulmonary Surfactants / therapeutic use
  • Respiration, Artificial
  • Suction


  • Pulmonary Surfactants