A pediatric protocol for management of extravasation injuries

Pediatr Nurs. 1993 Jul-Aug;19(4):355-8, 424.


The administration of bioactive agents through IV can lead to serious complications, including partial-or full-thickness skin loss, infection, nerve and tendon damage, or loss of limb. Children's Hospital of The King's Daughters (CHKD) implemented a protocol to uniformity identify and treat infiltrates in order to avoid these serious potential complications.

MeSH terms

  • Antidotes / therapeutic use*
  • Clinical Protocols*
  • Extravasation of Diagnostic and Therapeutic Materials / nursing*
  • Humans
  • Hyaluronoglucosaminidase / therapeutic use
  • Infant, Newborn
  • Infant, Premature
  • Nitroglycerin / therapeutic use
  • Phentolamine / therapeutic use
  • Skin Diseases / chemically induced
  • Skin Diseases / nursing


  • Antidotes
  • Hyaluronoglucosaminidase
  • Nitroglycerin
  • Phentolamine