Cervical neuroblastoma in eleven infants--a tumor with favorable prognosis. Clinical and radiologic (US, CT, MRI) findings

Pediatr Radiol. 1993;23(4):253-7. doi: 10.1007/BF02010908.


Cervical neuroblastoma, a disease primarily of infants, has a favorable prognosis. Eleven patients are reported. Clinical presentations (other than mass) included stridor and swallowing problems. Masses when felt were commonly mistaken for infectious adenitis. Imaging studies (US, CT, MRI) showed solid masses with vascular displacement and narrowing; intraspinal extension was absent though extension into the adjacent sites of mediastinum and skull occurred. Horner syndrome was seen in five patients with accompanying heterochromia iridis in one. Five tumors had calcification. A high index of suspicion will lead to biopsy and less delay in diagnosis once a mass is felt or imaged.

MeSH terms

  • Diagnosis, Differential
  • Female
  • Head and Neck Neoplasms / congenital
  • Head and Neck Neoplasms / diagnosis*
  • Head and Neck Neoplasms / diagnostic imaging
  • Humans
  • Infant
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Neuroblastoma / congenital
  • Neuroblastoma / diagnosis*
  • Neuroblastoma / diagnostic imaging
  • Prognosis
  • Tomography, X-Ray Computed
  • Ultrasonography