Wegener's granulomatosis presenting as a primary seizure disorder with brain lesions demonstrated by magnetic resonance imaging

Chest. 1993 Jan;103(1):316-8. doi: 10.1378/chest.103.1.316.


Since the earliest attempt by Klinger in 1931 to describe the systemic vasculitis subsequently characterized in 1936 by Wegener as Wegener's granulomatosis, this disorder has been reported to present in a number of differing fashions. No previous description relates Wegener's presenting as a seizure disorder, and no reports of MRI of the brain in such patients exists. We relate such a case, along with MRI findings, prior to and after treatment, with a review of neurologic manifestations of the disorder.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Brain Diseases / diagnosis*
  • Diagnosis, Differential
  • Granulomatosis with Polyangiitis / diagnosis*
  • Humans
  • Lung Diseases / diagnosis
  • Magnetic Resonance Imaging*
  • Male
  • Seizures / diagnosis*